This course introduces biotransport in terms of heat transfer, mass transfer, and fluid mechanics related to the human body. Some examples include cryosurgery of warts and drug delivery from skin patches. Beginning with biotransport problem formulation, the course explores software tools that enable mathematical modeling. Fundamental principles of model validation, mesh convergence, sensitivity analysis, and objective functions are presented. Several modeling labs are used to build software skill and explore various heat and mass transfer processes inside and around the human body. Medical device development concepts are presented, making a connection between modeling activities and product development. The final weeks of this class are dedicated to a final project on a student-selected topic. The student will complete an independent laboratory exercise or project.